• Kelch-like homologue 9 mutation is associated with an ...

    Genome-wide linkage analysis in this family revealed a new locus for distal myopathy at 9p21.2-p22.3 (multipoint logarithm of the odds ratio=4.21). By positional cloning we found a heterozygous mutation L95F in the Kelch-like homologue 9 gene, encoding a bric-a-brac Kelch protein. Molecular modelling indicated that the mutation may interfere ...Early Tracheostomy Is Associated With Shorter Ventilation ...Half of the ventilated patients with MC required a tracheostomy. Poorer health condition before the crisis and late-onset MG were associated with a tracheostomy. An early tracheostomy (≤ day 10), however, was associated with a shorter duration of MV and ICU-LOS by 2 weeks.

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  • Conformational ensembles of RNA oligonucleotides from ...

    Here, we consider the conformational ensembles of four RNA tetranucleotides by integrating available NMR data ( 9 – 11) with extensive atomistic MD simulations. Despite the lack of a biological relevance, RNA tetranucleotides serve as challenging model systems both from the experimental and computational point of view.Amber Advanced Tutorials - Tutorial 3 - MM-PBSA - …2016-12-13 · binding_energy.mmpbsa: verbose 0 parallel 0 prefix snapshot path ./ start 1 stop 200 offset 1 complex 1 receptor 1 ligand 1 compt ./ras-raf.prmtop recpt ./ras.prmtop ligpt ./raf.prmtop gc 0 as 0 dc 0 mm 1 gb 1 pb 1 ms 1 nm 0 @pb proc 2 refe 0 indi 1.0 exdi 80.0 scale 2 linit 1000 istrng 0.0 radiopt 0 arcres 0.0625 inp 1 surften 0.005 surfoff 0.00 ivcap 0 cutcap -1.0 …

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  • Early Tracheostomy Is Associated With Shorter Ventilation ...

    Half of the ventilated patients with MC required a tracheostomy. Poorer health condition before the crisis and late-onset MG were associated with a tracheostomy. An early tracheostomy (≤ day 10), however, was associated with a shorter duration of MV and ICU-LOS by 2 weeks.Kelch-like homologue 9 mutation is associated with an ...Genome-wide linkage analysis in this family revealed a new locus for distal myopathy at 9p21.2-p22.3 (multipoint logarithm of the odds ratio=4.21). By positional cloning we found a heterozygous mutation L95F in the Kelch-like homologue 9 gene, encoding a bric-a-brac Kelch protein. Molecular modelling indicated that the mutation may interfere ...

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  • In‐Situ Electronegativity and the Bridging of Chemical ...

    2021-10-20 · In the formation of B 2 H 6, changes in atomic charge and electronegativity go in opposite directions compared to what may be expected (Tables 2 and 3). Bridging H atoms in B 2 H 6 are more electronegative compared to atoms in isolation and in BH 3, even as they attain a negative charge in diborane.Fast thermo-optical modulators with doped-silicon heaters ...The 2-μm-waveband has been recognized as a potential telecommunication window for next-generation low-loss, low-latency optical communication. Thermo-optic (TO) modulators and switches, which are essential building blocks in a large-scale integrated photonic circuit, and their performances directly affect the energy consumption and reconfiguration time of an on-chip …

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  • Methane emission dynamics from a Danish landfill: The ...

    1. Introduction. Atmospheric methane (CH 4) concentration has steadily increased from 1650 ppbv to 1850 ppbv over the last 40 years, following the application of systematic measurements (IPCC, 2019a).Globally, this increase can be attributed – with a very high level of confidence – to anthropogenic activities such as agriculture and waste management, which contribute more …Spin Ice State in Frustrated Magnetic Pyrochlore MaterialsKnown spin ice–related materials include the frustrated pyrochlore magnet Tb 2 Ti 2 O 7, the behavior of which remains essentially mysterious ( 57, 58 ). Tb 2 Ti 2 O 7 has been described as a "cooperative paramagnet" ( 57 ), but it may also share some properties with the spin ice materials ( 34, 58 ).

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  • Kelch-like homologue 9 mutation is associated with an ...

    Genome-wide linkage analysis in this family revealed a new locus for distal myopathy at 9p21.2-p22.3 (multipoint logarithm of the odds ratio=4.21). By positional cloning we found a heterozygous mutation L95F in the Kelch-like homologue 9 gene, encoding a bric-a-brac Kelch protein. Molecular modelling indicated that the mutation may interfere .. crypting a cryptic allosteric pocket in H. pylori ...2021-12-10 · The D- to L-glutamate racemization activities of H. pylori GR was assayed through a previously established coupled-enzyme method, utilizing L-glutamate dehydrogenase and diaphorase 40. The H ...

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  • Genetically modified foods: safety, risks and public ...

    2012-12-19 · Genetic modification is a special set of gene technology that alters the genetic machinery of such living organisms as animals, plants or microorganisms. Combining genes from different organisms is known as recombinant DNA technology and the resulting organism is said to be ''Genetically modified (GM)'', ''Genetically engineered'' or ... | - Sun Yat-sen University66 Ling WH, Lougheed M, Suzuki H, Buchan A, Kodama T, Steinbrecher Urs. Oxidized or acetylated low density lipoprotein are rapidly cleared by the liver in mice with disruption of the scavenger receptor class A typeI/II gene.

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  • ESSD

    2021-10-26 · Abstract. Forest age can determine the capacity of a forest to uptake carbon from the atmosphere. However, a lack of global diagnostics that reflect the forest stage and associated disturbance regimes hampers the quantification of age-related differences in forest carbon dynamics. This study provides a new global distribution of forest age circa 2010, estimated …Department Biogeochemical Integration | People / …Scientist, Leader of the Global Diagnostics Ecohydrological and Biogeochemical Modelling group room: C 1.004 (tower) phone: +49 3641 576261 email: Martin.Jung(at)bgc-jena.mpg

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  • Spin Ice State in Frustrated Magnetic Pyrochlore Materials

    Known spin ice–related materials include the frustrated pyrochlore magnet Tb 2 Ti 2 O 7, the behavior of which remains essentially mysterious ( 57, 58 ). Tb 2 Ti 2 O 7 has been described as a "cooperative paramagnet" ( 57 ), but it may also share some properties with the spin ice materials ( 34, 58 ).—AMBERA3:MM-PBSA - ...2018-1-28 · : AMBER ADVANCED TUTORIAL 3: MM-PBSAPerl Version By Ross Walker & Thomas Steinbrecher Python Version By Dwight McGee, Bill Miller III, & Jason Swails 2018-01-28 06:39:37 : ; : mm_pbsaRAS-RAF, .

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  • AMBERA3:MM-PBSA|Jerkwin

    2018-1-28 · AMBERA3:MM-PBSA. Python Version By Dwight McGee, Bill Miller III, & Jason Swails. mm_pbsa RAS-RAF, . mmpbsa_py .M1_M2 - - Docin 2013-10-1 · M1_M2. (30973807) 、 Y2008C101)、 ( 2012GSF11908) ( 2011-28) : ( 1978,,,, ...

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  • ESSD

    2021-12-21 · Abstract. Land evaporation (ET) plays a crucial role in the hydrological and energy cycle. However, the widely used model-based products, even though helpful, are still subject to great uncertainties due to imperfect model parameterizations and forcing data. The lack of available observed data has further complicated estimation. | - Sun Yat-sen University66 Ling WH, Lougheed M, Suzuki H, Buchan A, Kodama T, Steinbrecher Urs. Oxidized or acetylated low density lipoprotein are rapidly cleared by the liver in mice with disruption of the scavenger receptor class A typeI/II gene.

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  • The NOX Family of ROS-Generating NADPH Oxidases ...

    2007-1-1 · For a long time, superoxide generation by an NADPH oxidase was considered as an oddity only found in professional phagocytes. Over the last years, six homologs of the cytochrome subunit of the phagocyte NADPH oxidase were found: NOX1, NOX3, NOX4, NOX5, DUOX1, and DUOX2. Together with the phagocyte NADPH oxidase itself (NOX2/gp91phox), the homologs …Thermally enhanced responsivity in an all-silicon optical ...We demonstrate a high responsivity all-silicon in-line optical power monitor by using the thermal effect to enhance the quantum efficiency of defect-mediated absorption at 1550 nm. The doping compensation technique is utilized to increase the density of lattice defects responsible for the sub-bandgap absorption and suppress the detrimental free carrier absorption.

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  • BG

    Abstract. Satellite-retrieved solar-induced chlorophyll fluorescence (SIF) has shown great potential to monitor the photosynthetic activity of terrestrial ecosystems. However, several issues, including low spatial and temporal resolution of the gridded datasets and high uncertainty of the individual retrievals, limit the applications of SIF crypting a cryptic allosteric pocket in H. pylori ...2021-12-10 · The D- to L-glutamate racemization activities of H. pylori GR was assayed through a previously established coupled-enzyme method, utilizing L-glutamate dehydrogenase and diaphorase 40. The H ...

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  • Methane emission dynamics from a Danish landfill: The ...

    1. Introduction. Atmospheric methane (CH 4) concentration has steadily increased from 1650 ppbv to 1850 ppbv over the last 40 years, following the application of systematic measurements (IPCC, 2019a).Globally, this increase can be attributed – with a very high level of confidence – to anthropogenic activities such as agriculture and waste management, which contribute more …Thermally enhanced responsivity in an all-silicon optical ...We demonstrate a high responsivity all-silicon in-line optical power monitor by using the thermal effect to enhance the quantum efficiency of defect-mediated absorption at 1550 nm. The doping compensation technique is utilized to increase the density of lattice defects responsible for the sub-bandgap absorption and suppress the detrimental free carrier absorption.

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  • Fast thermo-optical modulators with doped-silicon heaters ...

    The 2-μm-waveband has been recognized as a potential telecommunication window for next-generation low-loss, low-latency optical communication. Thermo-optic (TO) modulators and switches, which are essential building blocks in a large-scale integrated photonic circuit, and their performances directly affect the energy consumption and reconfiguration time of an on-chip …Relaxed Eddy Accumulation Simulations of Aerosol …2008-10-29 · Direct eddy-covariance measurements of aerosol number fluxes obtained during the 2007 CHATS field experiment in Dixon, California, USA are compared with relaxed eddy accumulation simulations using temperature and water vapour concentration as proxy scalars. After a brief discussion of the limited time response of the aerosol measurement, the …

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  • A New Family of Ultralow Loss Reversible Phase‐Change ...

    2020-7-9 · For Sb 2 S 3 we see the 3d5/2 peak at 529.40 eV, which agrees well with the range in the literature. A small amount of metallic Sb appears with a 3d5/2 peak at 528.28 eV. A 3d5/2 peak due to surface oxidation appears at 530.12 eV that corresponds to Sb 2 O 3, while elemental oxygen is at 529.67 eV.The sulfur 2p3/2 peak appeared at 161.46 eV.(PDF) Hurdle Technology : A novel approach for Food ...2022-1-3 · Results: Prevalence of stunting and severe stunting among adolescents was found 313 (25.47%) and 91 (7.40%) respectively. Prevalence of thinness and severe thinness were 279 (22.70%) and 89 (7.24% ...

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  • |

    66 Ling WH, Lougheed M, Suzuki H, Buchan A, Kodama T, Steinbrecher Urs. Oxidized or acetylated low density lipoprotein are rapidly cleared by the liver in mice with disruption of the scavenger receptor class A typeI/II gene.Spin Ice State in Frustrated Magnetic Pyrochlore MaterialsKnown spin ice–related materials include the frustrated pyrochlore magnet Tb 2 Ti 2 O 7, the behavior of which remains essentially mysterious ( 57, 58 ). Tb 2 Ti 2 O 7 has been described as a "cooperative paramagnet" ( 57 ), but it may also share some properties with the spin ice materials ( 34, 58 ).

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  • Accelerating Molecular Dynamics Enrichments of High ...

    2021-12-8 · Molecular docking algorithms are used to seek the most active compounds from a pool of ligands. In principle, molecular dynamics (MD) simulations with accurate physical potentials and sampling could yield better enrichments, but they are computationally expensive. Here, we describe a method called MELD-Bracket that utilizes biased replica exchange …Global maps of soil temperature - Lembrechts - - Global ...2021-12-29 · Here, we provide global maps of soil temperature and bioclimatic variables at a 1-km² resolution for 0–5 and 5–15 cm soil depth. These maps were created by calculating the difference (i.e., offset) between in-situ soil temperature measurements, based on time series from over 1200 1-km² pixels (summarized from 8500 unique temperature ...

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  • The IKK Complex, a Central Regulator of NF-κB Activation

    2021-11-11 · The interaction domain between the kinase subunits and NEMO was identified as a small peptide at the carboxyl terminus of IKKα and IKKβ. Interestingly, a cell-permeable 11‐amino-acid peptide derived from the carboxyl terminus of IKKβ (aa 735–745) behaves as an effective and specific inhibitor of NF-κB by inhibiting the IKK–NEMO interaction and proved to …Type 2 Diabetes Among Filipino American Adults in the ...2021-11-24 · Preventing Chronic Disease (PCD) is a peer-reviewed electronic journal established by the National Center for Chronic Disease Prevention and Health Promotion. PCD provides an open exchange of information and knowledge among researchers, practitioners, policy makers, and others who strive to improve the health of the public through chronic disease prevention.

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  • Genetically modified foods: safety, risks and public ...

    2012-12-19 · Genetic modification is a special set of gene technology that alters the genetic machinery of such living organisms as animals, plants or microorganisms. Combining genes from different organisms is known as recombinant DNA technology and the resulting organism is said to be ''Genetically modified (GM)'', ''Genetically engineered'' or ...Methane emission dynamics from a Danish landfill: The ...1. Introduction. Atmospheric methane (CH 4) concentration has steadily increased from 1650 ppbv to 1850 ppbv over the last 40 years, following the application of systematic measurements (IPCC, 2019a).Globally, this increase can be attributed – with a very high level of confidence – to anthropogenic activities such as agriculture and waste management, which contribute more …

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  • Thermally enhanced responsivity in an all-silicon optical ...

    We demonstrate a high responsivity all-silicon in-line optical power monitor by using the thermal effect to enhance the quantum efficiency of defect-mediated absorption at 1550 nm. The doping compensation technique is utilized to increase the density of lattice defects responsible for the sub-bandgap absorption and suppress the detrimental free carrier absorption.Stabilizing spin systems via symmetrically tailored RKKY ...2019-6-12 · The pristine Pt(111) surface is modeled by 40 Pt layers augmented by two vacuum regions. The magnetic Fe atoms are placed on the surface in the fcc-stacking position, using an embedding method ...

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  • Department Biogeochemical Integration | People / …

    Scientist, Leader of the Global Diagnostics Ecohydrological and Biogeochemical Modelling group room: C 1.004 (tower) phone: +49 3641 576261 email: Martin.Jung(at)bgc-jena.mpg ,PMF,,WHAM_rogerzhanglijie ...2012-10-30 · 4。。,。。,""。,,NPT,NVT,,。

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  • Conformational ensembles of RNA oligonucleotides from ...

    Here, we consider the conformational ensembles of four RNA tetranucleotides by integrating available NMR data ( 9 – 11) with extensive atomistic MD simulations. Despite the lack of a biological relevance, RNA tetranucleotides serve as challenging model systems both from the experimental and computational point of view.,PMF,,WHAM_(iSimuLy ...2018-9-26 · 4。。,。。,""。,,NPT,NVT,,。

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