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    2022-1-1 · The HER3/ERBB3 receptor is an oncogenic receptor tyrosine kinase that forms heterodimers with EGFR family members and is overexpressed in numerous cancers. HER3 overexpression associates with reduced survival and acquired resistance to targeted therapies, making it a potential therapeutic target in multiple cancer types. Here, we report on …Structure-guided discovery of a single-domain antibody ...However, there are only two GPCR monoclonal antibodies (mAbs) approved by the U.S. Food and Drug Administration, including erenumab, a calcitonin gene–related peptide receptor antagonist, for migraine prevention, and mogamulizumab, a CCR4 neutral binder with antibody-dependent cellular cytotoxicity in vivo, for adult T cell leukemia-lymphoma ...

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    1. Introduction. Nitrous oxide (N 2 O) is a potent greenhouse gas, which accounts for 7.9 per cent of the global anthropogenic greenhouse gas emissions in 2004 [] is also predicted to be the most dominant ozone-depleting substance in the twenty-first century [].Since 1750, the atmospheric N 2 O concentration has increased by about 16 per cent, from around 270 ppb, to …Member Groups | Institute Of Infectious Disease and ...2022-1-9 · Three multi-investigator groups that operate principally in the TB/HIV space: The South African TB Vaccine Initiative (SATVI), which includes Mark Hatherill (Director), Tom Scriba (Deputy Director) and Elisa Nemes; The Wellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa) which includes Robert Wilkinson (Director), Graeme Meintjes, Catherine …

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    2022-1-9 · Three multi-investigator groups that operate principally in the TB/HIV space: The South African TB Vaccine Initiative (SATVI), which includes Mark Hatherill (Director), Tom Scriba (Deputy Director) and Elisa Nemes; The Wellcome Centre for Infectious Diseases Research in Africa (CIDRI-Africa) which includes Robert Wilkinson (Director), Graeme Meintjes, Catherine …Potential use of polyphenols in the battle against COVID ...2020-4-1 · Polyphenols inhibiting SARS-CoV-2 RdRp. SARS-CoV-2 RdRp is a key target in the development of therapies against COVID-19. One of the antivirals temporarily approved by the FDA for the treatment of COVID-19, remdesivir is an analogue of adenosine and acts as a false substrate for RdRp [ 20, 52 ].

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    2004-10-13 · Liaw, J. S. & Berger, T. W. Dynamic synapse: a new concept of neural representation and computation. Hippocampus 6, 591–600 (1996). CAS Article Google ScholarPhysical reservoir computing—an introductory perspective ...2020-5-14 · [80] Kanao T., Suto H., Mizushima K., Goto H., Tanamoto T. and Nagasawa T. 2019 Reservoir computing on spin-torque oscillator array Phys. Rev. Appl. 12 024052. Go to reference in article Crossref Google Scholar [81] Riou M. et al 2019 Temporal pattern recognition with delayed-feedback spin-torque nano-oscillators Phys. Rev. Appl. 12 024049

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    2021-8-5 · Abstract Nonsteroidal anti-inflammatory drugs (NSAIDs) were thought to increase the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus entrance into cells. Hence, it was suggested i...Optimal referencing for stereo-electroencephalographic ...2018-12-1 · Stereo-encephalography (SEEG) is a different intracranial technique. Instead of placing electrodes on the lateral surface of the cortex, SEEG inserts depth electrodes into the human brain. These electrodes usually contain multiple recording contacts (typically 8–16 contacts with a 3.5 mm center-to-center distance) along each electrode''s shaft.

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  • Identification of Immunogenic MHC Class II Human HER3 ...

    2022-1-1 · The HER3/ERBB3 receptor is an oncogenic receptor tyrosine kinase that forms heterodimers with EGFR family members and is overexpressed in numerous cancers. HER3 overexpression associates with reduced survival and acquired resistance to targeted therapies, making it a potential therapeutic target in multiple cancer types. Here, we report on …A cis-regulatory-directed pipeline for the identification ...2021-12-15 · Embryogenesis is accomplished in a series of intricate morphogenetic events, driven by a complex network of genes that work in concert to control the formation of vital organs and body parts [].For instance, a cardiac gene regulatory network (GRN) regulates the development of the heart from a simple tubular structure into a pump under electrophysiological control [].

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    2019-9-1 · Fermentation has been used for "manufacturing" simple compounds (e.g. ethanol) and highly complex macromolecules (e.g. polysaccharides, proteins and enzymes), including bioactive metabolites (e.g. lactoferrin and flavonoids), from raw materials containing their precursors ().The newly generated substances can not only extend food shelf life and ensure safety, but also …6.3 :_china365love-CSDN2021-12-12 · ,。,。,,,。, ...

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